Climate factors influence seasonal influenza activity in Bangkok, Thailand

S3 Table. Parameters estimated by ARIMA(X) model with RMSE, AICc, MAPE, and coef- ficient values. (DOCX) Author Contributions Conceptualization: Nungruthai Suntronwong, Yong Poovorawan. Data curation: Nungruthai Suntronwong, Preeyaporn Vichaiwattana. Formal analysis: Nungruthai Suntronwong, Sompong Vongpunsawad, Yong Poovorawan. Funding acquisition: Nungruthai Suntronwong, Yong Poovorawan. Investigation: Nungruthai Suntronwong, Preeyaporn Vichaiwattana, Sirapa Klinfueng, Sumeth Korkong. Methodology: Nungruthai Suntronwong, Thanunrat Thongmee. Project administration: Yong Poovorawan. Resources: Yong Poovorawan. Software: Nungruthai Suntronwong. Supervision: Yong Poovorawan. Visualization: Nungruthai Suntronwong, Yong Poovorawan. Writing – original draft: Nungruthai Suntronwong, Sompong Vongpunsawad, Yong Poovorawan. Writing – review & editing: Nungruthai Suntronwong, Sompong Vongpunsawad, Yong Poovorawan. References 1. Troeger CE, Blacker BF, Khalil IA, Zimsen SR, Albertson SB, Abate D, et al. Mortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017: an analysis for the Global Bur- den of Disease Study 2017. Lancet Respir Med. 2019; 7(1):69–89. https://doi.org/10.1016/S2213-2600 (18)30496-X. PMID: 30553848. 2. Kamigaki T, Chaw L, Tan AG, Tamaki R, Alday PP, Javier JB, et al. Seasonality of Influenza and Respi- ratory Syncytial Viruses and the Effect of Climate Factors in Subtropical–Tropical Asia Using Influenza- Like Illness Surveillance Data, 2010–2012. PLoS One. 2016; 11(12):e0167712. https://doi.org/10.1371/

journal.pone.0167712. PMID: 28002419. 3. Lowen AC, Mubareka S, Steel J, Palese P. Influenza virus transmission is dependent on relative humid- ity and temperature. PLoS Pathog. 2007; 3(10):e151. https://doi.org/10.1371/journal.ppat.0030151. PMID: 17953482. 4. Lowen AC, Steel J, Mubareka S, Palese PJJov. High temperature (30˚C) blocks aerosol but not contact transmission of influenza virus. J Virol. 2008; 82(11):5650–2. https://doi.org/10.1128/JVI.00325-08. PMID: 18367530. 5. Lowen AC, Steel J. Roles of humidity and temperature in shaping influenza seasonality. J Virol. 2014; 88(14):7692–5. https://doi.org/10.1128/JVI.03544-13. PMID: 24789791. 6. Mubareka S, Lowen AC, Steel J, Coates AL, Garcı´a-Sastre A, Palese P. Transmission of influenza virus via aerosols and fomites in the guinea pig model. J Infect Dis. 2009; 199(6):858–65. https://doi. org/10.1086/597073. PMID: 19434931. 7. Shiu EY, Leung NH, Cowling B. Controversy around airborne versus droplet transmission of respiratory viruses: implication for infection prevention. Curr Opin Infect Dis. 2019; 32(4):372–9. https://doi.org/10. 1097/QCO.0000000000000563. PMID: 31259864. PLOS ONE Climate factors influence seasonal influenza activity in Bangkok, Thailand PLOS ONE | https://doi.org/10.1371/journal.pone.0239729 September 29, 2020 13 / 15