GMO approvals under pressure: How climate shocks shape policy across nations

PLOS One | https://doi.org/10.1371/journal.pone.0332298 October 22, 2025 18 / 20 shocks and drought-tolerant GMO traits. These results suggest that limited economic and technical capacity can constrain a country’s ability to adopt adaptive biotechnologies, even when faced with increasing climate risk. Second, the paper generates a Revealed Comparative Advantage (RCA) measure to to separate countries into two groups—those with a comparative advantage in GMO production and those without. The results show that climate shocks have more persistent and negative effects on GMO approvals in countries with a comparative disadvantage. Specifically, four years after a shock, these countries experience a notable decline in approvals, while countries with a comparative advantage do not. This supports the view that protectionist responses and weak specialization can amplify regulatory hesitation, leading to stalled innovation and potential global disputes over GMO policies. These findings carry important policy implications. As climate shocks become more frequent and severe, countries with limited technological capacity or weak comparative advantage in GMO production may fall further behind in adopting adaptive agricultural innovations. This delay not only undermines national food security efforts but may also deepen global disparities in resilience and productivity. To address this challenge, national policymakers should prioritize investments in agricultural research and development, strengthen biosafety regulatory frameworks, and enhance institutional capacity to

evaluate and deploy GMO technologies effectively. At the international level, cooperation is essential. Multilateral organizations, donors, and trade partners can help bridge these gaps by supporting harmonization of regulatory standards, facilitating access to pre-approved GMO events, and funding the technical infrastructure needed for risk assessment and monitoring. Encouraging transparent, science-based approval systems—particularly for GMO traits that have been vetted through international protocols—can reduce approval asymmetries and minimize delays in critical adaptive technologies. Additionally, trade agreements and global forums should consider the role of biotechnology in climate resilience and promote mechanisms that enable low- and middle-income countries to benefit from innovation diffusion. In sum, enhancing the institutional and regulatory founda- tions for GMO adoption in structurally disadvantaged regions is essential for building a more adaptive, inclusive, and secure global food system in the face of accelerating climate change. Supporting information S1 Data. Data R1. (CSV) Author contributions Conceptualization: Xiangwen Kong. Data curation: Xiangwen Kong. Formal analysis: Xiangwen Kong. Funding acquisition: Xiangwen Kong. Investigation: Xiangwen Kong. Methodology: Xiangwen Kong. Project administration: Xiangwen Kong. Resources: Xiangwen Kong. Software: Xiangwen Kong. Supervision: Xiangwen Kong. Validation: Xiangwen Kong. Visualization: Xiangwen Kong.