Does climate help modeling COVID-19 risk and to what extent?

S4 Fig. Feature impact scatters plot for the north and south hemispheres. SHAP value of each variable for all the single observations as a function of their relative value for the locations in the north (left) and south (left) hemispheres. The color transition on the vertical axis indi- cates value strength (red/high to blue/low). (TIF) S5 Fig. Feature importance analysis based on Lasso, Elastic Net, and Random Forest algo- rithms. For Lasso and Elastic Net we report their regression coefficients (red for negative val- ues and blue for positive). For the random forest tree, we use the Gini importance score. (TIF) S1 Table. Summary of peer-reviewed literature on research studies on the interrelationship between COVID-19 and environmental/climatic factors. (DOCX) S2 Table. Description of the variables used for the study. (DOCX) S3 Table. Descriptive statistics. (DOCX) Acknowledgments The findings presented in this study are solely the responsibility of the authors. An earlier ver- sion of this paper is available as a Research Square preprint (DOI: http://dx.doi.org/10.21203/ rs.3.rs-108398/v1). Author Contributions Conceptualization: Giovanni Scabbia, Antonio Sanfilippo, Annamaria Mazzoni. Data curation: Giovanni Scabbia, Annamaria Mazzoni, Dunia Bachour, Daniel Perez-Astu- dillo, Etienne Wey, Mathilde Marchand-Lasserre, Laurent Saboret. Formal analysis: Giovanni Scabbia, Antonio Sanfilippo, Annamaria Mazzoni. Funding acquisition: Antonio Sanfilippo. Investigation: Giovanni Scabbia, Antonio Sanfilippo, Annamaria Mazzoni.

Methodology: Giovanni Scabbia, Antonio Sanfilippo, Annamaria Mazzoni. Project administration: Antonio Sanfilippo. Resources: Giovanni Scabbia, Antonio Sanfilippo. Software: Giovanni Scabbia. Supervision: Antonio Sanfilippo, Veronica Bermudez. Validation: Giovanni Scabbia, Antonio Sanfilippo, Annamaria Mazzoni. Visualization: Giovanni Scabbia. Writing – original draft: Giovanni Scabbia, Antonio Sanfilippo, Annamaria Mazzoni, Dunia Bachour, Daniel Perez-Astudillo, Veronica Bermudez, Etienne Wey, Mathilde Marchand- Lasserre, Laurent Saboret. PLOS ONE Does climate help modeling COVID-19 risk and to what extent? PLOS ONE | https://doi.org/10.1371/journal.pone.0273078 September 7, 2022 23 / 27